Karyopharm Therapeutics Inc Major Shareholders & Ownership History
| Major Shareholder Name | Reporting Date | Shares Held | Market Value | Change in Shares | Ownership |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 08/14/2026 | 1.92 M | $18.73 M | 0.00% | 6.63% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 08/14/2026 | 1.52 M | $14.86 M | -15.78% | 5.26% |
| ACORN CAPITAL ADVISORS, LLC | 08/14/2026 | 1.52 M | $14.83 M | 427.44% | 5.25% |
| GOLDMAN SACHS GROUP INC | 08/14/2026 | 1.42 M | $13.92 M | 50.35% | 4.92% |
| BLACKROCK, INC. | 08/07/2026 | 1.42 M | $13.86 M | 479.34% | 4.90% |
| VANGUARD CAPITAL MANAGEMENT LLC | 08/13/2026 | 958.98 K | $9.37 M | 29.64% | 3.31% |
| CATALIO CAPITAL MANAGEMENT, LP | 08/14/2026 | 940.86 K | $9.19 M | 4.81% | 3.25% |
| AVIDITY PARTNERS MANAGEMENT LP | 08/14/2026 | 924.49 K | $9.03 M | 99.35% | 3.19% |
| T. ROWE PRICE INVESTMENT MANAGEMENT, INC. | 08/14/2026 | 786.31 K | $7.68 M | -49.01% | 2.72% |
| TWO SIGMA INVESTMENTS, LP | 08/14/2026 | 695.26 K | $6.79 M | 359.73% | 2.40% |
| KALEHUA CAPITAL MANAGEMENT LLC | 08/19/2026 | 685.64 K | $6.70 M | 100.00% | 2.37% |
| NEA MANAGEMENT COMPANY, LLC | 08/14/2026 | 576.78 K | $5.64 M | 100.00% | 1.99% |
| GEODE CAPITAL MANAGEMENT, LLC | 08/12/2026 | 531.23 K | $5.19 M | 157.71% | 1.84% |
| GHISALLO CAPITAL MANAGEMENT LLC | 08/14/2026 | 500.00 K | $4.89 M | 100.00% | 1.73% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 08/14/2026 | 484.80 K | $4.74 M | -43.95% | 1.68% |
| SOLEUS CAPITAL MANAGEMENT, L.P. | 08/11/2026 | 440.00 K | $4.30 M | 0.00% | 1.52% |
| UBS GROUP AG | 08/13/2026 | 353.55 K | $3.45 M | 82.22% | 1.22% |
| STATE STREET CORP | 08/07/2026 | 325.99 K | $3.18 M | 303.74% | 1.13% |
| AFFINITY ASSET ADVISORS, LLC | 08/13/2026 | 312.50 K | $3.05 M | -37.50% | 1.08% |
| BREVAN HOWARD CAPITAL MANAGEMENT LP | 08/14/2026 | 309.82 K | $3.03 M | 45.89% | 1.07% |
| MILLENNIUM MANAGEMENT LLC | 08/14/2026 | 305.68 K | $2.99 M | -27.32% | 1.06% |
| BOXER CAPITAL MANAGEMENT, LLC | 08/14/2026 | 302.54 K | $2.96 M | 0.00% | 1.05% |
| DAVIDSON KEMPNER CAPITAL MANAGEMENT LP | 08/14/2026 | 300.00 K | $2.93 M | 0.00% | 1.04% |
| ACADIAN ASSET MANAGEMENT LLC | 08/13/2026 | 299.00 K | $2.92 M | 20.10% | 1.03% |
| SILVERARC CAPITAL MANAGEMENT, LLC | 08/13/2026 | 297.46 K | $2.91 M | 100.00% | 1.03% |
| CAPTION MANAGEMENT, LLC | 08/14/2026 | 285.70 K | $2.79 M | -73.71% | 0.99% |
| EVERSEPT PARTNERS, LP | 08/14/2026 | 276.17 K | $2.70 M | 0.00% | 0.95% |
| TFG ASSET MANAGEMENT GP LTD | 08/13/2026 | 250.30 K | $2.45 M | 400.60% | 0.87% |
| JPMORGAN CHASE & CO | 08/12/2026 | 207.61 K | $2.09 M | 43,978.34% | 0.72% |
| MORGAN STANLEY | 08/13/2026 | 202.51 K | $1.98 M | 990.50% | 0.70% |
| TREXQUANT INVESTMENT LP | 08/14/2026 | 188.37 K | $1.84 M | -26.96% | 0.65% |
| BNP PARIBAS ARBITRAGE, SNC | 08/13/2026 | 188.04 K | $1.84 M | 223,754.76% | 0.65% |
| BARCLAYS PLC | 08/14/2026 | 165.90 K | $1.62 M | 2,134.70% | 0.57% |
| NORTHERN TRUST CORP | 08/13/2026 | 160.01 K | $1.56 M | 315.00% | 0.55% |
| VANGUARD FIDUCIARY TRUST CO | 08/13/2026 | 145.40 K | $1.42 M | 26.51% | 0.50% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 08/13/2026 | 134.82 K | $1.32 M | 100.00% | 0.47% |
| MARSHALL WACE, LLP | 08/13/2026 | 128.45 K | $1.25 M | 0.00% | 0.44% |
| RENAISSANCE TECHNOLOGIES LLC | 08/13/2026 | 108.21 K | $1.06 M | 2.66% | 0.37% |
| DLD ASSET MANAGEMENT, LP | 08/13/2026 | 101.50 K | $989.63 K | 100.00% | 0.35% |
| SILVERBACK ASSET MANAGEMENT LLC | 08/13/2026 | 100.00 K | $977.00 K | 0.00% | 0.35% |
| C WORLDWIDE GROUP HOLDING A/S | 08/04/2026 | 100.00 K | $977.00 K | 0.00% | 0.35% |
| JUMP FINANCIAL, LLC | 08/13/2026 | 94.00 K | $918.38 K | -64.14% | 0.32% |
| CAPTION MANAGEMENT, LLC | 08/14/2026 | 92.50 K | $903.73 K | -2.63% | 0.32% |
| INVESCO LTD. | 08/14/2026 | 90.30 K | $882.27 K | 439.51% | 0.31% |
| DLD ASSET MANAGEMENT, LP | 08/13/2026 | 80.10 K | $780.98 K | 100.00% | 0.28% |
| CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD. | 08/13/2026 | 76.40 K | $746.40 K | -3.39% | 0.26% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 08/14/2026 | 71.87 K | $702.20 K | 0.00% | 0.25% |
| J. GOLDMAN & CO LP | 08/14/2026 | 67.60 K | $660.45 K | 100.00% | 0.23% |
| J. GOLDMAN & CO LP | 08/14/2026 | 67.50 K | $659.48 K | 100.00% | 0.23% |
| SQUAREPOINT OPS LLC | 08/14/2026 | 63.80 K | $623.34 K | 100.00% | 0.22% |
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Karyopharm Therapeutics Inc institutional Ownership - FAQ's
During the previous two years, 154 institutional investors and hedge funds held shares of Karyopharm Therapeutics Inc. The most heavily invested institutionals were:
RA CAPITAL MANAGEMENT, L.P.: 1.92 M
ADAGE CAPITAL PARTNERS GP, L.L.C.: 1.52 M
ACORN CAPITAL ADVISORS, LLC: 1.52 M
GOLDMAN SACHS GROUP INC: 1.42 M
BlackRock, Inc.: 1.42 M
VANGUARD CAPITAL MANAGEMENT LLC: 958,979
73.18% of Karyopharm Therapeutics Inc stock is owned by institutional investors.
Institutional investors have bought a total of 32.63 M shares in the last 24 months. This purchase volume represents approximately $277.00 M in transactions.