Karyopharm Therapeutics Inc Major Shareholders & Ownership History
| Major Shareholder Name | Reporting Date | Shares Held | Market Value | Change in Shares | Ownership |
|---|---|---|---|---|---|
| COMMODORE CAPITAL LP | 05/15/2026 | 1.95 M | $10.86 M | 100.00% | 8.86% |
| RA CAPITAL MANAGEMENT, L.P. | 05/15/2026 | 1.92 M | $10.68 M | 100.00% | 8.71% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 05/15/2026 | 1.81 M | $10.06 M | 328.73% | 8.21% |
| T. ROWE PRICE INVESTMENT MANAGEMENT, INC. | 05/15/2026 | 1.54 M | $8.59 M | 3.40% | 7.01% |
| CAPTION MANAGEMENT, LLC | 05/15/2026 | 1.09 M | $6.05 M | 100.00% | 4.94% |
| GOLDMAN SACHS GROUP INC | 05/15/2026 | 947.58 K | $5.28 M | 100.00% | 4.30% |
| IKARIAN CAPITAL, LLC | 05/15/2026 | 920.00 K | $5.12 M | 100.00% | 4.18% |
| CATALIO CAPITAL MANAGEMENT, LP | 05/15/2026 | 897.71 K | $5.00 M | 527.84% | 4.08% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 05/15/2026 | 865.00 K | $4.82 M | 169.55% | 3.93% |
| 05/15/2026 | 750.00 K | $4.18 M | 100.00% | 3.41% | |
| 05/15/2026 | 739.75 K | $4.12 M | 100.00% | 3.36% | |
| IKARIAN CAPITAL, LLC | 05/15/2026 | 733.44 K | $4.09 M | 34.69% | 3.33% |
| AFFINITY ASSET ADVISORS, LLC | 05/14/2026 | 500.00 K | $2.79 M | -43.79% | 2.27% |
| JANE STREET GROUP, LLC | 05/12/2026 | 473.40 K | $2.64 M | 2,255.22% | 2.15% |
| AVIDITY PARTNERS MANAGEMENT LP | 05/28/2026 | 463.74 K | $2.58 M | 244.62% | 2.11% |
| SOLEUS CAPITAL MANAGEMENT, L.P. | 05/14/2026 | 440.00 K | $2.45 M | 0.00% | 2.00% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 05/15/2026 | 425.90 K | $2.37 M | 16.27% | 1.93% |
| MILLENNIUM MANAGEMENT LLC | 05/15/2026 | 420.57 K | $2.34 M | 100.00% | 1.91% |
| BOXER CAPITAL MANAGEMENT, LLC | 05/15/2026 | 302.54 K | $1.69 M | 19.80% | 1.37% |
| DAVIDSON KEMPNER CAPITAL MANAGEMENT LP | 05/15/2026 | 300.00 K | $1.67 M | -3.23% | 1.36% |
| ACORN CAPITAL ADVISORS, LLC | 05/15/2026 | 287.83 K | $1.60 M | 100.00% | 1.31% |
| EVERSEPT PARTNERS, LP | 05/15/2026 | 276.17 K | $1.54 M | 100.00% | 1.25% |
| BOOTHBAY FUND MANAGEMENT, LLC | 05/15/2026 | 268.30 K | $1.49 M | 100.00% | 1.22% |
| JUMP FINANCIAL, LLC | 05/14/2026 | 262.15 K | $1.46 M | 387.12% | 1.19% |
| CITADEL ADVISORS LLC | 05/15/2026 | 258.20 K | $1.44 M | 694.46% | 1.17% |
| TREXQUANT INVESTMENT LP | 05/15/2026 | 257.90 K | $1.44 M | 517.98% | 1.17% |
| ALLY BRIDGE GROUP (NY) LLC | 05/18/2026 | 250.00 K | $1.39 M | 100.00% | 1.14% |
| CITADEL ADVISORS LLC | 05/15/2026 | 249.30 K | $1.39 M | 249.65% | 1.13% |
| ACADIAN ASSET MANAGEMENT LLC | 05/13/2026 | 248.96 K | $1.38 M | 6,581.62% | 1.13% |
| BLACKROCK, INC. | 05/13/2026 | 244.90 K | $1.36 M | -1.07% | 1.11% |
| DIADEMA PARTNERS LP | 05/15/2026 | 241.30 K | $1.34 M | 100.00% | 1.10% |
| BOOTHBAY FUND MANAGEMENT, LLC | 05/15/2026 | 213.81 K | $1.19 M | 47.83% | 0.97% |
| BREVAN HOWARD CAPITAL MANAGEMENT LP | 05/15/2026 | 212.37 K | $1.18 M | 100.00% | 0.96% |
| GEODE CAPITAL MANAGEMENT, LLC | 05/15/2026 | 206.13 K | $1.15 M | 9.80% | 0.94% |
| ADAR1 CAPITAL MANAGEMENT, LLC | 05/18/2026 | 205.20 K | $1.14 M | 100.00% | 0.93% |
| UBS GROUP AG | 05/05/2026 | 194.02 K | $1.08 M | 119.34% | 0.88% |
| GROUP ONE TRADING, L.P. | 05/13/2026 | 191.53 K | $1.07 M | 87.00% | 0.87% |
| XTX TOPCO LTD | 05/15/2026 | 164.44 K | $915.95 K | 1,281.41% | 0.75% |
| TWO SIGMA INVESTMENTS, LP | 05/15/2026 | 151.23 K | $842.36 K | 1.64% | 0.69% |
| ADAR1 CAPITAL MANAGEMENT, LLC | 05/18/2026 | 136.74 K | $761.62 K | 173.47% | 0.62% |
| MARSHALL WACE, LLP | 05/15/2026 | 128.45 K | $715.47 K | 0.00% | 0.58% |
| VANGUARD FIDUCIARY TRUST CO | 05/08/2026 | 114.93 K | $640.18 K | 100.00% | 0.52% |
| ENGINEERS GATE MANAGER LP | 05/15/2026 | 112.43 K | $626.25 K | 100.00% | 0.51% |
| JANE STREET GROUP, LLC | 05/12/2026 | 105.90 K | $589.87 K | 198.04% | 0.48% |
| RENAISSANCE TECHNOLOGIES LLC | 05/14/2026 | 105.41 K | $587.16 K | 75.94% | 0.48% |
| BALYASNY ASSET MANAGEMENT L.P. | 05/15/2026 | 100.00 K | $557.00 K | 100.00% | 0.45% |
| SILVERBACK ASSET MANAGEMENT LLC | 05/21/2026 | 100.00 K | $557.00 K | 100.00% | 0.45% |
| C WORLDWIDE GROUP HOLDING A/S | 05/06/2026 | 100.00 K | $557.00 K | 0.00% | 0.45% |
| CAPTION MANAGEMENT, LLC | 05/15/2026 | 95.00 K | $529.15 K | 100.00% | 0.43% |
| MILLENNIUM MANAGEMENT LLC | 05/15/2026 | 91.00 K | $506.87 K | 100.00% | 0.41% |
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Karyopharm Therapeutics Inc institutional Ownership - FAQ's
During the previous two years, 119 institutional investors and hedge funds held shares of Karyopharm Therapeutics Inc. The most heavily invested institutionals were:
COMMODORE CAPITAL LP: 1.95 M
RA CAPITAL MANAGEMENT, L.P.: 1.92 M
ADAGE CAPITAL PARTNERS GP, L.L.C.: 1.81 M
T. Rowe Price Investment Management, Inc.: 1.54 M
GOLDMAN SACHS GROUP INC: 947,579
Catalio Capital Management, LP: 897,709
83.27% of Karyopharm Therapeutics Inc stock is owned by institutional investors.
Institutional investors have bought a total of 28.15 M shares in the last 24 months. This purchase volume represents approximately $239.03 M in transactions.