Karyopharm Therapeutics Inc. Major Shareholders & Ownership History
| Major Shareholder Name | Reporting Date | Shares Held | Market Value | Change in Shares | Ownership |
|---|---|---|---|---|---|
| T. ROWE PRICE INVESTMENT MANAGEMENT, INC. | 11/14/2025 | 700.99 K | $4.59 M | -3.81% | 8.13% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 11/14/2025 | 421.32 K | $2.76 M | 0.00% | 4.89% |
| VANGUARD GROUP INC | 11/07/2025 | 408.22 K | $2.67 M | -21.23% | 4.74% |
| BLACKROCK, INC. | 11/12/2025 | 231.95 K | $1.52 M | -1.98% | 2.69% |
| AFFINITY ASSET ADVISORS, LLC | 11/13/2025 | 157.60 K | $1.03 M | 0.06% | 1.83% |
| CATALIO CAPITAL MANAGEMENT, LP | 11/14/2025 | 142.98 K | $935.12 K | -2.07% | 1.66% |
| AVIDITY PARTNERS MANAGEMENT LP | 11/14/2025 | 134.57 K | $880.06 K | 0.00% | 1.56% |
| MARSHALL WACE, LLP | 11/13/2025 | 128.45 K | $840.07 K | 0.00% | 1.49% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 11/14/2025 | 127.80 K | $835.81 K | 100.00% | 1.48% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 11/14/2025 | 118.90 K | $777.61 K | 616.27% | 1.38% |
| C WORLDWIDE GROUP HOLDING A/S | 11/05/2025 | 100.00 K | $654.00 K | 0.00% | 1.16% |
| GEODE CAPITAL MANAGEMENT, LLC | 11/12/2025 | 93.29 K | $610.25 K | 1.58% | 1.08% |
| GROUP ONE TRADING, L.P. | 11/12/2025 | 68.44 K | $447.57 K | -30.10% | 0.79% |
| RENAISSANCE TECHNOLOGIES LLC | 11/13/2025 | 64.71 K | $423.23 K | -1.67% | 0.75% |
| UBS GROUP AG | 11/13/2025 | 59.69 K | $390.34 K | -63.13% | 0.69% |
| STATE STREET CORP | 11/14/2025 | 46.34 K | $303.08 K | 39.19% | 0.54% |
| CITADEL ADVISORS LLC | 11/14/2025 | 46.30 K | $302.80 K | 100.00% | 0.54% |
| CITADEL ADVISORS LLC | 11/14/2025 | 45.70 K | $298.88 K | 181.68% | 0.53% |
| SILVERBACK ASSET MANAGEMENT LLC | 11/13/2025 | 40.00 K | $261.60 K | -42.86% | 0.46% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 11/14/2025 | 35.34 K | $231.12 K | 100.00% | 0.41% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 11/14/2025 | 34.87 K | $228.07 K | -7.83% | 0.40% |
| IKARIAN CAPITAL, LLC | 11/14/2025 | 27.26 K | $178.26 K | 0.00% | 0.32% |
| BAIRD FINANCIAL GROUP, INC. | 11/13/2025 | 25.93 K | $169.60 K | 146.22% | 0.30% |
| MORGAN STANLEY | 11/14/2025 | 25.77 K | $168.51 K | 2.69% | 0.30% |
| ADAR1 CAPITAL MANAGEMENT, LLC | 11/14/2025 | 25.00 K | $163.50 K | 100.00% | 0.29% |
| GOLDMAN SACHS GROUP INC | 11/14/2025 | 24.89 K | $162.75 K | -77.25% | 0.29% |
| NORTHERN TRUST CORP | 11/14/2025 | 18.88 K | $123.45 K | -0.18% | 0.22% |
| BELVEDERE TRADING LLC | 10/27/2025 | 14.56 K | $95.24 K | 100.00% | 0.17% |
| XTX TOPCO LTD | 11/14/2025 | 14.40 K | $94.19 K | 10.31% | 0.17% |
| GSA CAPITAL PARTNERS LLP | 11/07/2025 | 14.08 K | $92.00 K | 1.31% | 0.16% |
| JANE STREET GROUP, LLC | 11/14/2025 | 12.90 K | $84.37 K | 100.00% | 0.15% |
| BANK OF NEW YORK MELLON CORP | 11/03/2025 | 11.09 K | $72.50 K | 0.00% | 0.13% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 11/14/2025 | 10.89 K | $72.00 K | 0.00% | 0.13% |
| ROYAL BANK OF CANADA | 11/14/2025 | 6.73 K | $44.00 K | -9.36% | 0.08% |
| SIMPLEX TRADING, LLC | 11/12/2025 | 5.86 K | $38.00 K | -28.80% | 0.07% |
| BARCLAYS PLC | 11/12/2025 | 4.11 K | $26.87 K | -22.95% | 0.05% |
| TD WATERHOUSE CANADA INC. | 11/03/2025 | 3.20 K | $19.86 K | 0.00% | 0.04% |
| TOWER RESEARCH CAPITAL LLC (TRC) | 11/14/2025 | 1.09 K | $7.12 K | 28.12% | 0.01% |
| FMR LLC | 11/13/2025 | 679 | $4.44 K | -11.24% | 0.01% |
| JPMORGAN CHASE & CO | 11/26/2025 | 550 | $3.60 K | -99.79% | 0.01% |
| CITIGROUP INC | 11/10/2025 | 513 | $3.36 K | -92.71% | 0.01% |
| BELVEDERE TRADING LLC | 10/27/2025 | 500 | $3.27 K | 100.00% | 0.01% |
| ADVISOR GROUP HOLDINGS, INC. | 11/14/2025 | 346 | $2.41 K | 0.00% | 0.00% |
| QUENT CAPITAL, LLC | 10/27/2025 | 231 | $1.51 K | 100.00% | 0.00% |
| RISE ADVISORS, LLC | 10/08/2025 | 131 | $857 | 100.00% | 0.00% |
| MB, LEVIS & ASSOCIATES, LLC | 10/15/2025 | 100 | $654 | 0.00% | 0.00% |
| BANK OF AMERICA CORP /DE/ | 11/14/2025 | 94 | $615 | -99.94% | 0.00% |
| HARBOUR INVESTMENTS, INC. | 11/12/2025 | 85 | $556 | 0.00% | 0.00% |
| BNP PARIBAS ARBITRAGE, SNC | 11/13/2025 | 82 | $536 | -99.72% | 0.00% |
| FORTITUDE FAMILY OFFICE, LLC | 10/17/2025 | 81 | $530 | 0.00% | 0.00% |
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Karyopharm Therapeutics Inc. institutional Ownership - FAQ's
During the previous two years, 95 institutional investors and hedge funds held shares of Karyopharm Therapeutics Inc.. The most heavily invested institutionals were:
T. Rowe Price Investment Management, Inc.: 700,992
ADAGE CAPITAL PARTNERS GP, L.L.C.: 421,322
VANGUARD GROUP INC: 408,222
BlackRock, Inc.: 231,951
Catalio Capital Management, LP: 142,984
Avidity Partners Management LP: 134,566
34.20% of Karyopharm Therapeutics Inc. stock is owned by institutional investors.
Institutional investors have bought a total of 13.75 M shares in the last 24 months. This purchase volume represents approximately $87.72 M in transactions.