Ionis Pharmaceuticals, Inc. Major Shareholders & Ownership History
| Major Shareholder Name | Reporting Date | Shares Held | Market Value | Change in Shares | Ownership |
|---|---|---|---|---|---|
| DLD ASSET MANAGEMENT, LP | 11/13/2025 | 25.00 M | $34.63 M | 100.00% | 15.71% |
| FMR LLC | 11/13/2025 | 23.69 M | $1.55 B | 0.19% | 14.89% |
| VANGUARD GROUP INC | 11/07/2025 | 16.48 M | $1.08 B | -1.39% | 10.36% |
| T. ROWE PRICE INVESTMENT MANAGEMENT, INC. | 11/14/2025 | 13.16 M | $860.73 M | -18.02% | 8.27% |
| CAPITAL WORLD INVESTORS | 11/13/2025 | 12.72 M | $832.32 M | 1.46% | 7.99% |
| BLACKROCK, INC. | 11/12/2025 | 10.45 M | $683.50 M | -4.12% | 6.57% |
| WELLINGTON MANAGEMENT GROUP LLP | 11/14/2025 | 6.59 M | $431.04 M | 3.83% | 4.14% |
| LOMBARD ODIER ASSET MANAGEMENT (EUROPE) LTD | 11/14/2025 | 6.49 M | $8.96 M | 100.00% | 4.08% |
| BELLEVUE GROUP AG | 11/14/2025 | 6.24 M | $408.51 M | -20.49% | 3.92% |
| STATE STREET CORP | 11/14/2025 | 4.39 M | $287.11 M | -3.13% | 2.76% |
| DEEP TRACK CAPITAL, LP | 11/14/2025 | 3.81 M | $249.13 M | -22.15% | 2.39% |
| GEODE CAPITAL MANAGEMENT, LLC | 11/12/2025 | 3.07 M | $200.63 M | 6.06% | 1.93% |
| TWEEDY, BROWNE CO LLC | 11/20/2025 | 2.90 M | $189.80 M | 0.32% | 1.82% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 11/14/2025 | 2.73 M | $178.58 M | -12.68% | 1.72% |
| CITADEL ADVISORS LLC | 11/14/2025 | 2.40 M | $157.14 M | 60.68% | 1.51% |
| TWO SIGMA ADVISERS, LP | 11/14/2025 | 2.07 M | $135.62 M | -22.29% | 1.30% |
| DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) | 11/14/2025 | 1.98 M | $129.51 M | 100.00% | 1.24% |
| TWO SIGMA INVESTMENTS, LP | 11/14/2025 | 1.58 M | $103.10 M | -11.88% | 0.99% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 11/10/2025 | 1.52 M | $99.44 M | 2.16% | 0.96% |
| PICTET ASSET MANAGEMENT HOLDING SA | 11/18/2025 | 1.39 M | $90.48 M | 128.89% | 0.88% |
| AMERICAN CENTURY COMPANIES INC | 11/12/2025 | 1.37 M | $89.77 M | 190.27% | 0.86% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 11/14/2025 | 1.32 M | $86.03 M | -65.39% | 0.83% |
| ROYAL BANK OF CANADA | 11/14/2025 | 1.23 M | $80.24 M | 53.34% | 0.77% |
| MORGAN STANLEY | 11/14/2025 | 1.18 M | $77.22 M | -13.35% | 0.74% |
| UBS ASSET MANAGEMENT AMERICAS INC | 11/14/2025 | 1.15 M | $75.51 M | 45.90% | 0.73% |
| MACQUARIE GROUP LTD | 11/13/2025 | 1.13 M | $74.05 M | -21.07% | 0.71% |
| VESTAL POINT CAPITAL, LP | 11/14/2025 | 1.08 M | $70.33 M | 115.00% | 0.68% |
| GROUPAMA ASSET MANAGMENT | 12/01/2025 | 1.06 M | $37.44 M | -8.54% | 0.67% |
| BNP PARIBAS ASSET MANAGEMENT HOLDING S.A. | 11/07/2025 | 1.06 M | $69.32 M | -21.55% | 0.67% |
| UBS GROUP AG | 11/13/2025 | 1.05 M | $68.49 M | -31.54% | 0.66% |
| POLAR CAPITAL HOLDINGS PLC | 11/14/2025 | 1.03 M | $67.62 M | 3.36% | 0.65% |
| TD ASSET MANAGEMENT INC | 11/10/2025 | 960.27 K | $62.82 M | -13.07% | 0.60% |
| MARSHALL WACE, LLP | 11/13/2025 | 958.83 K | $62.73 M | 7,219.31% | 0.60% |
| ARTISAN PARTNERS LIMITED PARTNERSHIP | 11/12/2025 | 890.07 K | $58.23 M | 150.75% | 0.56% |
| CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD. | 11/13/2025 | 878.16 K | $57.45 M | 230.39% | 0.55% |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 10/29/2025 | 862.59 K | $56.43 M | 66.14% | 0.54% |
| BANK OF AMERICA CORP /DE/ | 11/14/2025 | 855.30 K | $55.95 M | -14.12% | 0.54% |
| NORTHERN TRUST CORP | 11/14/2025 | 844.94 K | $55.28 M | 3.77% | 0.53% |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 11/14/2025 | 803.05 K | $52.54 M | -6.04% | 0.50% |
| MILLENNIUM MANAGEMENT LLC | 11/14/2025 | 779.57 K | $51.00 M | -70.58% | 0.49% |
| GOLDMAN SACHS GROUP INC | 11/14/2025 | 777.57 K | $50.87 M | -0.05% | 0.49% |
| AMERIPRISE FINANCIAL INC | 11/14/2025 | 765.82 K | $50.10 M | 108.04% | 0.48% |
| BALYASNY ASSET MANAGEMENT L.P. | 11/14/2025 | 760.11 K | $49.73 M | -1.11% | 0.48% |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | 11/14/2025 | 750.00 K | $49.07 M | 100.00% | 0.47% |
| BANK OF MONTREAL /CAN/ | 11/13/2025 | 747.40 K | $48.90 M | 54.65% | 0.47% |
| NOMURA HOLDINGS INC | 11/14/2025 | 733.40 K | $47.98 M | 2,180.40% | 0.46% |
| BARCLAYS PLC | 11/12/2025 | 714.05 K | $46.71 M | 22.42% | 0.45% |
| ARK INVESTMENT MANAGEMENT LLC | 11/12/2025 | 631.22 K | $41.29 M | -29.89% | 0.40% |
| D. E. SHAW & CO., INC. | 11/14/2025 | 630.94 K | $41.28 M | 100.00% | 0.40% |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 11/13/2025 | 630.14 K | $41.22 M | 100.00% | 0.40% |
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Ionis Pharmaceuticals, Inc. institutional Ownership - FAQ's
During the previous two years, 621 institutional investors and hedge funds held shares of Ionis Pharmaceuticals, Inc.. The most heavily invested institutionals were:
DLD Asset Management, LP: 25 M
FMR LLC: 23.69 M
VANGUARD GROUP INC: 16.48 M
T. Rowe Price Investment Management, Inc.: 13.16 M
Capital World Investors: 12.72 M
BlackRock, Inc.: 10.45 M
125.77% of Ionis Pharmaceuticals, Inc. stock is owned by institutional investors.
Institutional investors have bought a total of 236.54 M shares in the last 24 months. This purchase volume represents approximately $16.36 B in transactions.