IONS
Income statement / Annual
Last year (2025), Ionis Pharmaceuticals Inc's total revenue was $944.00 M,
an increase of 33.87% from the previous year.
In 2025, Ionis Pharmaceuticals Inc's net income was -$381.00 M.
See Ionis Pharmaceuticals Inc,s key income statements, including revenue, expenses, profit, and income.
| Period |
FY-2025
|
FY-2024
|
FY-2023
|
FY-2022
|
FY-2021
|
FY-2020
|
FY-2019
|
FY-2018
|
FY-2017
|
FY-2016
|
| Period Ended |
12/31/2025 |
12/31/2024 |
12/31/2023 |
12/31/2022 |
12/31/2021 |
12/31/2020 |
12/31/2019 |
12/31/2018 |
12/31/2017 |
12/31/2016 |
| Operating Revenue |
$944.00 M |
$705.14 M |
$787.65 M |
$587.37 M |
$810.46 M |
$729.26 M |
$1.12 B |
$599.67 M |
$514.18 M |
$372.78 M |
| Cost of Revenue |
$16.00 M
|
$11.22 M
|
$9.13 M
|
$14.12 M
|
$10.84 M
|
$11.95 M
|
$4.38 M
|
$1.82 M
|
$0.00
|
$0.00
|
| Gross Profit |
$928.00 M
|
$693.92 M
|
$778.51 M
|
$573.25 M
|
$799.61 M
|
$717.32 M
|
$1.12 B
|
$597.85 M
|
$514.18 M
|
$372.78 M
|
| Gross Profit Ratio |
0.98
|
0.98
|
0.99
|
0.98
|
0.99
|
0.98
|
1
|
1
|
1
|
1
|
| Research and Development Expenses |
$916.00 M
|
$901.53 M
|
$899.63 M
|
$833.00 M
|
$643.00 M
|
$535.00 M
|
$466.00 M
|
$414.60 M
|
$374.64 M
|
$344.32 M
|
| General & Administrative Expenses |
$0.00
|
$267.50 M
|
$232.60 M
|
$150.30 M
|
$170.90 M
|
$332.20 M
|
$286.64 M
|
$244.62 M
|
$108.49 M
|
$48.62 M
|
| Selling & Marketing Expenses |
$0.00
|
$0.00
|
$0.00
|
-$5.00 K
|
$0.00
|
$0.00
|
$0.00
|
$0.00
|
$0.00
|
$0.00
|
| Selling, General & Administrative Expenses |
$394.00 M
|
$267.50 M
|
$232.60 M
|
$150.30 M
|
$170.90 M
|
$332.20 M
|
$286.64 M
|
$244.62 M
|
$108.49 M
|
$48.62 M
|
| Other Expenses |
$0.00
|
-$26.00 K
|
$19.00 K
|
$147.00 K
|
$15.90 M
|
$22.20 M
|
-$312.00 K
|
$0.00
|
$0.00
|
$0.00
|
| Operating Expenses |
$1.31 B
|
$1.17 B
|
$1.13 B
|
$983.44 M
|
$829.80 M
|
$889.40 M
|
$752.33 M
|
$659.23 M
|
$483.13 M
|
$392.94 M
|
| Cost And Expenses |
$1.33 B
|
$1.18 B
|
$1.14 B
|
$997.56 M
|
$840.64 M
|
$901.35 M
|
$756.72 M
|
$661.05 M
|
$483.13 M
|
$392.94 M
|
| Interest Income |
$0.00
|
$107.02 M
|
$89.04 M
|
$25.33 M
|
$10.04 M
|
$30.56 M
|
$52.21 M
|
$30.19 M
|
$8.18 M
|
$5.42 M
|
| Interest Expense |
$73.00 M
|
$90.45 M
|
$81.46 M
|
$8.12 M
|
$9.35 M
|
$9.51 M
|
$48.77 M
|
$44.79 M
|
$44.75 M
|
$38.80 M
|
| Depreciation & Amortization |
$20.26 M
|
$21.99 M
|
$22.50 M
|
$22.11 M
|
$19.56 M
|
$17.16 M
|
$15.99 M
|
$12.53 M
|
$8.35 M
|
$9.03 M
|
| EBITDA |
-$286.75 M |
-$353.72 M |
-$235.87 M |
-$227.76 M |
-$5.19 M |
-$111.19 M |
$367.20 M |
-$18.84 M |
$36.34 M |
-$9.64 M |
| EBITDA Ratio |
-0.3
|
-0.5
|
-0.3
|
-0.39
|
-0.01
|
-0.15
|
0.33
|
-0.03
|
0.07
|
-0.03
|
| Operating Income Ratio |
-0.4
|
-0.67
|
-0.45
|
-0.7
|
-0.04
|
-0.24
|
0.33
|
-0.1
|
0.06
|
-0.05
|
| Total Other Income/Expenses Net |
$2.00 M
|
$15.01 M
|
$19.77 M
|
$152.21 M
|
$1.04 M
|
$37.53 M
|
-$27.12 M
|
-$14.78 M
|
-$47.81 M
|
-$37.31 M
|
| Income Before Tax |
-$380.00 M
|
-$460.07 M
|
-$333.97 M
|
-$257.99 M
|
-$29.15 M
|
-$134.55 M
|
$338.77 M
|
-$76.16 M
|
-$16.76 M
|
-$57.47 M
|
| Income Before Tax Ratio |
-0.4
|
-0.65
|
-0.42
|
-0.44
|
-0.04
|
-0.18
|
0.3
|
-0.13
|
-0.03
|
-0.15
|
| Income Tax Expense |
$1.00 M
|
-$6.17 M
|
$32.32 M
|
$11.74 M
|
-$551.00 K
|
$345.19 M
|
$51.51 M
|
-$291.14 M
|
-$5.98 M
|
$2.93 M
|
| Net Income |
-$381.00 M
|
-$453.90 M
|
-$366.29 M
|
-$269.72 M
|
-$28.60 M
|
-$444.26 M
|
$278.14 M
|
$273.74 M
|
$346.00 K
|
-$60.40 M
|
| Net Income Ratio |
-0.4
|
-0.64
|
-0.47
|
-0.46
|
-0.04
|
-0.61
|
0.25
|
0.46
|
0
|
-0.16
|
| EPS |
-2.38 |
-3.04 |
-2.56 |
-1.9 |
-0.2 |
-3.18 |
2.1 |
2.07 |
-0.0481 |
-0.72 |
| EPS Diluted |
-2.38 |
-3.04 |
-2.56 |
-1.9 |
-0.2 |
-3.18 |
2.06 |
2.04 |
-0.0473 |
-0.72 |
| Weighted Average Shares Out |
$160.00 M
|
$149.51 M
|
$143.00 M
|
$141.85 M
|
$141.02 M
|
$139.61 M
|
$140.00 M
|
$132.32 M
|
$124.02 M
|
$120.80 M
|
| Weighted Average Shares Out Diluted |
$160.00 M
|
$149.51 M
|
$143.19 M
|
$141.85 M
|
$141.02 M
|
$139.61 M
|
$142.87 M
|
$134.06 M
|
$126.10 M
|
$120.93 M
|
| Link |
|
|
|
|
|
|
|
|
|
|
