Spero Therapeutics Inc Major Shareholders & Ownership History
| Major Shareholder Name | Reporting Date | Shares Held | Market Value | Change in Shares | Ownership |
|---|---|---|---|---|---|
| GSK PLC | 05/14/2026 | 9.19 M | $21.51 M | 0.00% | 16.41% |
| PFIZER INC | 05/12/2026 | 2.36 M | $5.50 M | 0.00% | 4.22% |
| 05/15/2026 | 1.80 M | $4.21 M | 100.00% | 3.21% | |
| RENAISSANCE TECHNOLOGIES LLC | 05/14/2026 | 1.19 M | $2.78 M | -7.06% | 2.12% |
| ALPHABET INC. | 05/08/2026 | 889.98 K | $2.08 M | 0.00% | 1.59% |
| TWO SIGMA INVESTMENTS, LP | 05/15/2026 | 885.63 K | $2.07 M | 137.71% | 1.58% |
| GEODE CAPITAL MANAGEMENT, LLC | 05/15/2026 | 519.92 K | $1.22 M | -1.75% | 0.93% |
| BLACKROCK, INC. | 05/13/2026 | 433.20 K | $1.01 M | -0.10% | 0.77% |
| ANSON FUNDS MANAGEMENT LP | 05/19/2026 | 421.96 K | $987.38 K | -32.49% | 0.75% |
| CITADEL ADVISORS LLC | 05/15/2026 | 376.46 K | $880.91 K | -5.38% | 0.67% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 05/15/2026 | 333.12 K | $779.49 K | 13.42% | 0.59% |
| GSA CAPITAL PARTNERS LLP | 05/08/2026 | 278.30 K | $651.00 K | 55.54% | 0.50% |
| VANGUARD FIDUCIARY TRUST CO | 05/08/2026 | 264.12 K | $618.03 K | 100.00% | 0.47% |
| STATE STREET CORP | 05/15/2026 | 214.75 K | $502.52 K | 2.19% | 0.38% |
| IONIC CAPITAL MANAGEMENT LLC | 05/15/2026 | 195.94 K | $458.50 K | 0.00% | 0.35% |
| SQUAREPOINT OPS LLC | 05/15/2026 | 194.30 K | $454.66 K | 62.68% | 0.35% |
| MARSHALL WACE, LLP | 05/15/2026 | 157.07 K | $367.55 K | 100.00% | 0.28% |
| NORTHERN TRUST CORP | 05/14/2026 | 120.98 K | $283.10 K | 0.00% | 0.22% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 05/15/2026 | 114.80 K | $268.63 K | 0.00% | 0.20% |
| JANE STREET GROUP, LLC | 05/12/2026 | 106.35 K | $248.85 K | -32.84% | 0.19% |
| SHAY CAPITAL LLC | 05/15/2026 | 70.35 K | $164.63 K | 16.69% | 0.13% |
| POINT72 ASSET MANAGEMENT, L.P. | 05/15/2026 | 59.67 K | $139.62 K | 36.92% | 0.11% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 05/15/2026 | 48.50 K | $113.49 K | 100.00% | 0.09% |
| INVESCO LTD. | 05/12/2026 | 45.37 K | $106.18 K | 83.66% | 0.08% |
| QUADRATURE CAPITAL LTD | 05/15/2026 | 40.13 K | $93.90 K | 6.16% | 0.07% |
| OMERS ADMINISTRATION CORP | 05/15/2026 | 39.40 K | $92.20 K | -69.95% | 0.07% |
| JANE STREET GROUP, LLC | 05/12/2026 | 38.50 K | $90.09 K | -0.26% | 0.07% |
| JANE STREET GROUP, LLC | 05/12/2026 | 37.80 K | $88.45 K | 100.00% | 0.07% |
| VERDAD ADVISERS, LP | 05/15/2026 | 33.46 K | $78.29 K | 100.00% | 0.06% |
| CAPITAL ASSET ADVISORY SERVICES LLC | 04/24/2026 | 32.55 K | $92.44 K | 0.00% | 0.06% |
| SIMPLEX TRADING, LLC | 05/14/2026 | 30.30 K | $70.91 K | -15.08% | 0.05% |
| THREE SEASONS WEALTH, LLC | 05/05/2026 | 30.00 K | $70.20 K | 0.00% | 0.05% |
| DIMENSIONAL FUND ADVISORS LP | 05/07/2026 | 29.77 K | $69.21 K | 0.00% | 0.05% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 05/15/2026 | 28.57 K | $66.84 K | 0.00% | 0.05% |
| CITADEL ADVISORS LLC | 05/15/2026 | 26.70 K | $62.48 K | 100.00% | 0.05% |
| VANGUARD GLOBAL ADVISERS, LLC | 05/08/2026 | 25.45 K | $59.54 K | 100.00% | 0.05% |
| CITADEL ADVISORS LLC | 05/15/2026 | 22.50 K | $52.65 K | -69.22% | 0.04% |
| SCHONFELD STRATEGIC ADVISORS LLC | 05/15/2026 | 20.31 K | $47.53 K | 100.00% | 0.04% |
| CITIGROUP INC | 05/11/2026 | 19.14 K | $44.78 K | 112,458.82% | 0.03% |
| ASSENAGON ASSET MANAGEMENT S.A. | 04/20/2026 | 18.64 K | $43.61 K | 0.00% | 0.03% |
| 04/21/2026 | 17.03 K | $37.63 K | 0.00% | 0.03% | |
| OCCUDO QUANTITATIVE STRATEGIES LP | 05/15/2026 | 16.42 K | $41.22 K | 100.00% | 0.03% |
| INTREPID FAMILY OFFICE LLC | 05/15/2026 | 16.28 K | $38.09 K | -90.13% | 0.03% |
| JONES FINANCIAL COMPANIES LLLP | 05/15/2026 | 7.68 K | $17.89 K | 18.54% | 0.01% |
| FNY INVESTMENT ADVISERS, LLC | 04/15/2026 | 5.30 K | $12.00 K | 0.00% | 0.01% |
| MORGAN STANLEY | 05/15/2026 | 4.55 K | $10.65 K | 1,354.31% | 0.01% |
| UBS GROUP AG | 05/05/2026 | 3.01 K | $7.04 K | -97.42% | 0.01% |
| ADVISOR GROUP HOLDINGS, INC. | 05/15/2026 | 290 | $678 | 0.00% | 0.00% |
| JPMORGAN CHASE & CO | 05/13/2026 | 236 | $529 | -95.61% | 0.00% |
| WELLS FARGO & COMPANY/MN | 05/11/2026 | 200 | $468 | 0.00% | 0.00% |
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Spero Therapeutics Inc institutional Ownership - FAQ's
During the previous two years, 76 institutional investors and hedge funds held shares of Spero Therapeutics Inc. The most heavily invested institutionals were:
GSK PLC: 9.19 M
PFIZER INC: 2.36 M
RENAISSANCE TECHNOLOGIES LLC: 1.19 M
Alphabet Inc.: 889,979
TWO SIGMA INVESTMENTS, LP: 885,631
GEODE CAPITAL MANAGEMENT, LLC: 519,922
36.85% of Spero Therapeutics Inc stock is owned by institutional investors.
Institutional investors have bought a total of 25.17 M shares in the last 24 months. This purchase volume represents approximately $58.40 M in transactions.