Spero Therapeutics Inc Major Shareholders & Ownership History
| Major Shareholder Name | Reporting Date | Shares Held | Market Value | Change in Shares | Ownership |
|---|---|---|---|---|---|
| GSK PLC | 02/12/2026 | 9.19 M | $21.41 M | 100.00% | 16.33% |
| PFIZER INC | 02/12/2026 | 2.36 M | $5.50 M | 0.00% | 4.20% |
| VANGUARD GROUP INC | 01/29/2026 | 2.08 M | $4.85 M | 4.70% | 3.70% |
| RENAISSANCE TECHNOLOGIES LLC | 02/12/2026 | 1.28 M | $2.98 M | -11.93% | 2.27% |
| ALPHABET INC. | 02/13/2026 | 889.98 K | $2.07 M | 0.00% | 1.58% |
| ANSON FUNDS MANAGEMENT LP | 02/17/2026 | 625.06 K | $1.46 M | -61.02% | 1.11% |
| GEODE CAPITAL MANAGEMENT, LLC | 02/09/2026 | 529.20 K | $1.23 M | 0.33% | 0.94% |
| BLACKROCK, INC. | 02/12/2026 | 433.62 K | $1.01 M | -0.27% | 0.77% |
| CITADEL ADVISORS LLC | 02/17/2026 | 397.86 K | $927.02 K | 100.00% | 0.71% |
| TWO SIGMA INVESTMENTS, LP | 02/17/2026 | 372.57 K | $868.09 K | 654.21% | 0.66% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 02/17/2026 | 293.70 K | $684.32 K | 100.00% | 0.52% |
| EAM INVESTORS, LLC | 02/12/2026 | 218.08 K | $508.14 K | -22.79% | 0.39% |
| TWO SIGMA ADVISERS, LP | 02/17/2026 | 216.60 K | $504.68 K | 100.00% | 0.38% |
| STATE STREET CORP | 02/13/2026 | 210.15 K | $489.65 K | 10.05% | 0.37% |
| IONIC CAPITAL MANAGEMENT LLC | 02/17/2026 | 195.94 K | $456.54 K | -6.13% | 0.35% |
| GSA CAPITAL PARTNERS LLP | 02/06/2026 | 178.93 K | $417.00 K | 67.39% | 0.32% |
| INTREPID FAMILY OFFICE LLC | 02/17/2026 | 165.00 K | $384.45 K | 50.00% | 0.29% |
| JANE STREET GROUP, LLC | 02/12/2026 | 158.34 K | $368.94 K | 268.34% | 0.28% |
| SEI INVESTMENTS CO | 02/13/2026 | 132.01 K | $307.58 K | 100.00% | 0.23% |
| OMERS ADMINISTRATION CORP | 02/13/2026 | 131.13 K | $305.53 K | 100.00% | 0.23% |
| NORTHERN TRUST CORP | 02/17/2026 | 120.98 K | $281.89 K | -6.68% | 0.22% |
| SQUAREPOINT OPS LLC | 02/13/2026 | 119.43 K | $278.28 K | 100.00% | 0.21% |
| UBS GROUP AG | 01/29/2026 | 116.45 K | $271.32 K | 329.68% | 0.21% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 02/17/2026 | 114.80 K | $267.48 K | 0.00% | 0.20% |
| ADAR1 CAPITAL MANAGEMENT, LLC | 02/18/2026 | 113.84 K | $265.25 K | -1.47% | 0.20% |
| CITADEL ADVISORS LLC | 02/17/2026 | 73.10 K | $170.32 K | 33.39% | 0.13% |
| SHAY CAPITAL LLC | 02/17/2026 | 60.29 K | $140.47 K | -5.31% | 0.11% |
| POINT72 ASSET MANAGEMENT, L.P. | 02/17/2026 | 43.58 K | $101.54 K | 100.00% | 0.08% |
| JANE STREET GROUP, LLC | 02/12/2026 | 38.60 K | $89.94 K | 100.00% | 0.07% |
| QUADRATURE CAPITAL LTD | 02/17/2026 | 37.80 K | $88.07 K | 100.00% | 0.07% |
| SIMPLEX TRADING, LLC | 02/11/2026 | 35.69 K | $83.15 K | 368.44% | 0.06% |
| CAPITAL ASSET ADVISORY SERVICES LLC | 01/09/2026 | 32.55 K | $81.70 K | 0.00% | 0.06% |
| AXXCESS WEALTH MANAGEMENT, LLC | 02/19/2026 | 32.55 K | $75.84 K | 0.00% | 0.06% |
| THREE SEASONS WEALTH, LLC | 01/15/2026 | 30.00 K | $69.90 K | 0.00% | 0.05% |
| DIMENSIONAL FUND ADVISORS LP | 02/12/2026 | 29.77 K | $69.05 K | 2.67% | 0.05% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 02/13/2026 | 28.57 K | $66.56 K | 0.00% | 0.05% |
| INVESCO LTD. | 02/19/2026 | 24.71 K | $57.56 K | 11.79% | 0.04% |
| MILLENNIUM MANAGEMENT LLC | 02/17/2026 | 24.11 K | $56.17 K | 100.00% | 0.04% |
| ASSENAGON ASSET MANAGEMENT S.A. | 01/09/2026 | 18.64 K | $43.42 K | -49.62% | 0.03% |
| 02/17/2026 | 17.03 K | $39.67 K | 7.92% | 0.03% | |
| XTX TOPCO LTD | 02/17/2026 | 15.18 K | $35.36 K | -55.10% | 0.03% |
| TEXAS YALE CAPITAL CORP. | 02/10/2026 | 10.00 K | $23.30 K | 0.00% | 0.02% |
| TOWER RESEARCH CAPITAL LLC (TRC) | 02/17/2026 | 7.22 K | $16.81 K | 100.00% | 0.01% |
| JONES FINANCIAL COMPANIES LLLP | 02/17/2026 | 6.48 K | $15.09 K | 100.00% | 0.01% |
| JPMORGAN CHASE & CO | 02/11/2026 | 5.37 K | $12.52 K | 2,176.69% | 0.01% |
| FNY INVESTMENT ADVISERS, LLC | 01/16/2026 | 5.30 K | $12.00 K | 0.00% | 0.01% |
| CULLEN/FROST BANKERS, INC. | 02/06/2026 | 3.00 K | $6.99 K | 100.00% | 0.01% |
| BANK OF AMERICA CORP /DE/ | 02/17/2026 | 744 | $1.73 K | 1.50% | 0.00% |
| MORGAN STANLEY | 02/13/2026 | 313 | $729 | -99.28% | 0.00% |
| ADVISOR GROUP HOLDINGS, INC. | 02/17/2026 | 290 | $675 | 0.00% | 0.00% |
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Spero Therapeutics Inc institutional Ownership - FAQ's
During the previous two years, 77 institutional investors and hedge funds held shares of Spero Therapeutics Inc. The most heavily invested institutionals were:
Capital Asset Advisory Services LLC: 32,548
Three Seasons Wealth, LLC: 30,000
Assenagon Asset Management S.A.: 18,636
FNY Investment Advisers, LLC: 5,300
UBS Group AG: 3,009
Farther Finance Advisors, LLC: 10
37.53% of Spero Therapeutics Inc stock is owned by institutional investors.
Institutional investors have bought a total of 25.02 M shares in the last 24 months. This purchase volume represents approximately $58.06 M in transactions.