Spero Therapeutics, Inc. Major Shareholders & Ownership History
| Major Shareholder Name | Reporting Date | Shares Held | Market Value | Change in Shares | Ownership |
|---|---|---|---|---|---|
| PFIZER INC | 11/13/2025 | 2.36 M | $4.44 M | 0.00% | 4.22% |
| VANGUARD GROUP INC | 11/07/2025 | 1.99 M | $3.74 M | 2.02% | 3.55% |
| ANSON FUNDS MANAGEMENT LP | 11/14/2025 | 1.60 M | $3.01 M | -0.74% | 2.86% |
| RENAISSANCE TECHNOLOGIES LLC | 11/13/2025 | 1.45 M | $2.73 M | 74.58% | 2.59% |
| ALPHABET INC. | 11/07/2025 | 889.98 K | $1.67 M | 0.00% | 1.59% |
| GEODE CAPITAL MANAGEMENT, LLC | 11/12/2025 | 527.48 K | $991.89 K | 3.29% | 0.94% |
| BLACKROCK, INC. | 11/12/2025 | 434.77 K | $817.36 K | 0.00% | 0.78% |
| EAM INVESTORS, LLC | 11/14/2025 | 282.45 K | $531.00 K | 18.11% | 0.50% |
| IONIC CAPITAL MANAGEMENT LLC | 11/14/2025 | 208.73 K | $392.40 K | 39.15% | 0.37% |
| STATE STREET CORP | 11/14/2025 | 190.95 K | $358.99 K | 24.44% | 0.34% |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 11/13/2025 | 150.52 K | $282.97 K | 100.00% | 0.27% |
| NORTHERN TRUST CORP | 11/14/2025 | 129.64 K | $243.73 K | 28.57% | 0.23% |
| ADAR1 CAPITAL MANAGEMENT, LLC | 11/14/2025 | 115.54 K | $217.21 K | -19.72% | 0.21% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 11/14/2025 | 114.80 K | $215.82 K | 0.00% | 0.20% |
| INTREPID FAMILY OFFICE LLC | 11/14/2025 | 110.00 K | $206.80 K | 100.00% | 0.20% |
| GSA CAPITAL PARTNERS LLP | 11/07/2025 | 106.89 K | $201.00 K | 100.00% | 0.19% |
| SHAY CAPITAL LLC | 11/14/2025 | 63.67 K | $119.69 K | 100.00% | 0.11% |
| CITADEL ADVISORS LLC | 11/14/2025 | 54.80 K | $103.02 K | -60.06% | 0.10% |
| TWO SIGMA INVESTMENTS, LP | 11/14/2025 | 49.40 K | $92.87 K | 100.00% | 0.09% |
| MORGAN STANLEY | 11/14/2025 | 43.38 K | $81.55 K | 370.43% | 0.08% |
| JANE STREET GROUP, LLC | 11/14/2025 | 42.99 K | $80.82 K | 100.00% | 0.08% |
| CUBIST SYSTEMATIC STRATEGIES, LLC | 11/14/2025 | 40.85 K | $76.79 K | 50.50% | 0.07% |
| AMERICAN CENTURY COMPANIES INC | 11/12/2025 | 40.22 K | $75.61 K | 100.00% | 0.07% |
| ASSENAGON ASSET MANAGEMENT S.A. | 10/07/2025 | 36.99 K | $69.55 K | 100.00% | 0.07% |
| XTX TOPCO LTD | 11/14/2025 | 33.80 K | $63.55 K | -2.17% | 0.06% |
| CAPITAL ASSET ADVISORY SERVICES LLC | 10/02/2025 | 32.55 K | $61.19 K | 0.00% | 0.06% |
| AXXCESS WEALTH MANAGEMENT, LLC | 11/07/2025 | 32.55 K | $61.19 K | 0.00% | 0.06% |
| RANGELEY CAPITAL, LLC | 11/14/2025 | 30.00 K | $56.40 K | 100.00% | 0.05% |
| THREE SEASONS WEALTH, LLC | 10/17/2025 | 30.00 K | $56.40 K | 0.00% | 0.05% |
| DIMENSIONAL FUND ADVISORS LP | 11/12/2025 | 28.99 K | $54.86 K | 100.00% | 0.05% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 11/10/2025 | 28.57 K | $53.70 K | 0.00% | 0.05% |
| UBS GROUP AG | 11/13/2025 | 27.10 K | $50.95 K | 230.74% | 0.05% |
| INVESCO LTD. | 11/13/2025 | 22.10 K | $41.55 K | 47.65% | 0.04% |
| GROUP ONE TRADING, L.P. | 11/12/2025 | 16.88 K | $31.73 K | 104.87% | 0.03% |
| 11/13/2025 | 15.78 K | $29.66 K | 100.00% | 0.03% | |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 11/14/2025 | 10.90 K | $20.49 K | -77.62% | 0.02% |
| TEXAS YALE CAPITAL CORP. | 11/07/2025 | 10.00 K | $18.80 K | 0.00% | 0.02% |
| SIMPLEX TRADING, LLC | 11/12/2025 | 7.62 K | $14.00 K | -74.88% | 0.01% |
| BANK OF AMERICA CORP /DE/ | 11/14/2025 | 733 | $1.38 K | -86.99% | 0.00% |
| FMR LLC | 11/13/2025 | 550 | $1.03 K | 100.00% | 0.00% |
| ADVISOR GROUP HOLDINGS, INC. | 11/14/2025 | 290 | $545 | 0.00% | 0.00% |
| JPMORGAN CHASE & CO | 11/26/2025 | 236 | $444 | 0.00% | 0.00% |
| WELLS FARGO & COMPANY/MN | 11/13/2025 | 200 | $376 | 0.00% | 0.00% |
| ROCKEFELLER CAPITAL MANAGEMENT L.P. | 11/14/2025 | 200 | $376 | 100.00% | 0.00% |
| US BANCORP \DE\ | 11/12/2025 | 151 | $284 | 0.00% | 0.00% |
| NEWEDGE ADVISORS, LLC | 11/17/2025 | 100 | $188 | 0.00% | 0.00% |
| BNP PARIBAS ARBITRAGE, SNC | 11/13/2025 | 40 | $75 | 0.00% | 0.00% |
| SBI SECURITIES CO., LTD. | 11/05/2025 | 10 | $19 | -83.87% | 0.00% |
| CULLEN/FROST BANKERS, INC. | 10/31/2025 | 0 | $0 | -100.00% | 0.00% |
| RAYMOND JAMES FINANCIAL INC | 11/14/2025 | 0 | $0 | -100.00% | 0.00% |
Explore Related Stocks for Market Trends
Explore our related stocks for the latest market trends and stock news to stay informed and make better decisions.
Spero Therapeutics, Inc. institutional Ownership - FAQ's
During the previous two years, 69 institutional investors and hedge funds held shares of Spero Therapeutics, Inc.. The most heavily invested institutionals were:
PFIZER INC: 2.36 M
VANGUARD GROUP INC: 1.99 M
Anson Funds Management LP: 1.6 M
RENAISSANCE TECHNOLOGIES LLC: 1.45 M
Alphabet Inc.: 889,979
GEODE CAPITAL MANAGEMENT, LLC: 527,477
20.18% of Spero Therapeutics, Inc. stock is owned by institutional investors.
Institutional investors have bought a total of 15.30 M shares in the last 24 months. This purchase volume represents approximately $31.36 M in transactions.