Spero Therapeutics Inc Major Shareholders & Ownership History
| Major Shareholder Name | Reporting Date | Shares Held | Market Value | Change in Shares | Ownership |
|---|---|---|---|---|---|
| GSK PLC | 08/13/2026 | 9.19 M | $20.31 M | 0.00% | 15.85% |
| PFIZER INC | 08/13/2026 | 2.36 M | $5.34 M | 0.00% | 4.08% |
| VANGUARD CAPITAL MANAGEMENT LLC | 08/13/2026 | 2.04 M | $4.50 M | 13.13% | 3.51% |
| RENAISSANCE TECHNOLOGIES LLC | 08/13/2026 | 947.90 K | $2.09 M | -20.29% | 1.64% |
| ALPHABET INC. | 08/07/2026 | 889.98 K | $1.97 M | 0.00% | 1.54% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 08/14/2026 | 759.29 K | $1.68 M | 127.94% | 1.31% |
| BLACKROCK, INC. | 08/07/2026 | 594.40 K | $1.31 M | 37.21% | 1.03% |
| GEODE CAPITAL MANAGEMENT, LLC | 08/12/2026 | 566.33 K | $1.25 M | 8.93% | 0.98% |
| RAYMOND JAMES FINANCIAL INC | 08/14/2026 | 521.71 K | $1.15 M | 100.00% | 0.90% |
| TWO SIGMA INVESTMENTS, LP | 08/14/2026 | 382.81 K | $846.02 K | -56.78% | 0.66% |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 08/13/2026 | 332.97 K | $735.86 K | 100.00% | 0.57% |
| VANGUARD FIDUCIARY TRUST CO | 08/13/2026 | 287.65 K | $635.70 K | 8.91% | 0.50% |
| GSA CAPITAL PARTNERS LLP | 08/06/2026 | 285.91 K | $632.00 K | 2.73% | 0.49% |
| DIMENSIONAL FUND ADVISORS LP | 08/11/2026 | 274.82 K | $607.62 K | 823.21% | 0.47% |
| GOLDMAN SACHS GROUP INC | 08/14/2026 | 256.99 K | $567.94 K | 100.00% | 0.44% |
| STATE STREET CORP | 08/07/2026 | 214.75 K | $474.60 K | 0.00% | 0.37% |
| JANE STREET GROUP, LLC | 08/14/2026 | 158.10 K | $349.39 K | 48.66% | 0.27% |
| UBS GROUP AG | 08/13/2026 | 139.68 K | $308.69 K | 4,542.07% | 0.24% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 08/14/2026 | 114.80 K | $253.71 K | 0.00% | 0.20% |
| NORTHERN TRUST CORP | 08/13/2026 | 108.27 K | $239.29 K | -10.51% | 0.19% |
| POINT72 ASSET MANAGEMENT, L.P. | 08/14/2026 | 104.38 K | $230.67 K | 74.93% | 0.18% |
| IONIC CAPITAL MANAGEMENT LLC | 08/14/2026 | 102.70 K | $226.96 K | -47.59% | 0.18% |
| FEDERATION DES CAISSES DESJARDINS DU QUEBEC | 08/14/2026 | 91.90 K | $202.18 K | 100.00% | 0.16% |
| SHAY CAPITAL LLC | 08/14/2026 | 72.39 K | $159.98 K | 2.90% | 0.12% |
| CITADEL ADVISORS LLC | 09/02/2026 | 65.60 K | $144.98 K | 191.56% | 0.11% |
| INVESCO LTD. | 08/14/2026 | 64.25 K | $141.98 K | 41.59% | 0.11% |
| SIMPLEX TRADING, LLC | 08/12/2026 | 61.31 K | $135.50 K | 102.32% | 0.11% |
| VERDAD ADVISERS, LP | 08/14/2026 | 51.34 K | $113.45 K | 53.44% | 0.09% |
| XTX TOPCO LTD | 08/14/2026 | 50.54 K | $111.69 K | 100.00% | 0.09% |
| JANE STREET GROUP, LLC | 08/14/2026 | 47.10 K | $104.09 K | 24.60% | 0.08% |
| AMERICAN CENTURY COMPANIES INC | 08/12/2026 | 36.81 K | $81.35 K | 100.00% | 0.06% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 08/14/2026 | 34.60 K | $76.47 K | -28.66% | 0.06% |
| CAPITAL ASSET ADVISORY SERVICES LLC | 08/14/2026 | 32.55 K | $71.93 K | 0.00% | 0.06% |
| AXXCESS WEALTH MANAGEMENT, LLC | 07/28/2026 | 32.55 K | $71.93 K | 100.00% | 0.06% |
| DLK INVESTMENT MANAGEMENT, LLC | 07/14/2026 | 31.36 K | $40.76 K | 100.00% | 0.05% |
| THREE SEASONS WEALTH, LLC | 08/13/2026 | 30.00 K | $66.30 K | 0.00% | 0.05% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 08/14/2026 | 28.57 K | $63.13 K | 0.00% | 0.05% |
| SIXTH STREET PARTNERS MANAGEMENT COMPANY, L.P. | 08/14/2026 | 28.57 K | $63.13 K | 100.00% | 0.05% |
| JANE STREET GROUP, LLC | 08/14/2026 | 26.80 K | $59.23 K | -30.39% | 0.05% |
| VANGUARD GLOBAL ADVISERS, LLC | 08/13/2026 | 25.45 K | $56.24 K | 0.00% | 0.04% |
| GLOBAL RETIREMENT PARTNERS, LLC | 08/06/2026 | 25.00 K | $55.25 K | 100.00% | 0.04% |
| OPPENHEIMER & CO INC | 08/03/2026 | 22.85 K | $50.50 K | 100.00% | 0.04% |
| MILLENNIUM MANAGEMENT LLC | 08/14/2026 | 19.30 K | $42.65 K | 100.00% | 0.03% |
| ASSENAGON ASSET MANAGEMENT S.A. | 08/21/2026 | 18.64 K | $41.19 K | 0.00% | 0.03% |
| SUSQUEHANNA PORTFOLIO STRATEGIES, LLC | 08/14/2026 | 17.63 K | $38.96 K | 100.00% | 0.03% |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 08/14/2026 | 16.10 K | $35.57 K | 100.00% | 0.03% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 08/14/2026 | 13.70 K | $30.28 K | 100.00% | 0.02% |
| QUBE RESEARCH & TECHNOLOGIES LTD | 08/14/2026 | 13.64 K | $30.15 K | 100.00% | 0.02% |
| SG AMERICAS SECURITIES, LLC | 08/07/2026 | 11.27 K | $25.00 K | 100.00% | 0.02% |
| GROUP ONE TRADING, L.P. | 08/14/2026 | 10.87 K | $24.02 K | 100.00% | 0.02% |
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Spero Therapeutics Inc institutional Ownership - FAQ's
During the previous two years, 88 institutional investors and hedge funds held shares of Spero Therapeutics Inc. The most heavily invested institutionals were:
GSK PLC: 9.19 M
PFIZER INC: 2.36 M
VANGUARD CAPITAL MANAGEMENT LLC: 2.04 M
RENAISSANCE TECHNOLOGIES LLC: 947,904
Alphabet Inc.: 889,979
SUSQUEHANNA INTERNATIONAL GROUP, LLP: 759,290
37.06% of Spero Therapeutics Inc stock is owned by institutional investors.
Institutional investors have bought a total of 27.83 M shares in the last 24 months. This purchase volume represents approximately $64.57 M in transactions.