Septerna Inc. Major Shareholders & Ownership History
| Major Shareholder Name | Reporting Date | Shares Held | Market Value | Change in Shares | Ownership |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 05/15/2026 | 7.00 M | $168.11 M | 0.00% | 15.81% |
| TRV GP V, LLC | 05/07/2026 | 6.22 M | $149.36 M | 0.00% | 14.04% |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 05/15/2026 | 4.40 M | $105.63 M | -8.61% | 9.93% |
| TRV GP VI, LLC | 05/07/2026 | 4.21 M | $101.21 M | 0.00% | 9.52% |
| SAMSARA BIOCAPITAL, LLC | 05/15/2026 | 3.15 M | $75.67 M | 0.00% | 7.12% |
| GOLDMAN SACHS GROUP INC | 05/15/2026 | 2.91 M | $69.84 M | 7.05% | 6.57% |
| SIREN, L.L.C. | 05/14/2026 | 2.00 M | $48.06 M | 0.00% | 4.52% |
| BLACKROCK, INC. | 05/13/2026 | 1.82 M | $43.79 M | 1.16% | 4.12% |
| BVF INC/IL | 05/15/2026 | 1.35 M | $32.52 M | -21.36% | 3.06% |
| AVORO CAPITAL ADVISORS LLC | 05/15/2026 | 1.34 M | $32.14 M | 0.00% | 3.02% |
| 05/15/2026 | 1.20 M | $28.76 M | 100.00% | 2.70% | |
| ADAR1 CAPITAL MANAGEMENT, LLC | 05/18/2026 | 1.09 M | $26.19 M | -5.86% | 2.46% |
| PRIMECAP MANAGEMENT CO/CA/ | 05/11/2026 | 1.05 M | $25.20 M | 92.06% | 2.37% |
| JANUS HENDERSON GROUP PLC | 05/18/2026 | 890.75 K | $21.33 M | 100.00% | 2.01% |
| FIRST LIGHT ASSET MANAGEMENT, LLC | 05/15/2026 | 732.86 K | $17.61 M | 18.05% | 1.66% |
| GEODE CAPITAL MANAGEMENT, LLC | 05/15/2026 | 645.15 K | $15.51 M | 12.64% | 1.46% |
| STATE STREET CORP | 05/15/2026 | 631.45 K | $15.17 M | 16.93% | 1.43% |
| CASDIN CAPITAL, LLC | 05/15/2026 | 553.27 K | $13.30 M | 0.00% | 1.25% |
| VR ADVISER, LLC | 05/15/2026 | 506.06 K | $12.16 M | -17.15% | 1.14% |
| CATALIO CAPITAL MANAGEMENT, LP | 05/15/2026 | 294.36 K | $7.07 M | 0.00% | 0.67% |
| SOLEUS CAPITAL MANAGEMENT, L.P. | 05/14/2026 | 275.00 K | $6.61 M | -28.27% | 0.62% |
| BALYASNY ASSET MANAGEMENT L.P. | 05/15/2026 | 236.68 K | $5.69 M | 6,527.81% | 0.53% |
| UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH | 05/11/2026 | 224.00 K | $5.38 M | 0.58% | 0.51% |
| 05/08/2026 | 195.04 K | $4.69 M | 100.00% | 0.44% | |
| 05/15/2026 | 194.54 K | $4.67 M | 0.00% | 0.44% | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 05/15/2026 | 181.58 K | $4.36 M | -3.02% | 0.41% |
| NORTHERN TRUST CORP | 05/14/2026 | 164.53 K | $3.95 M | 6.70% | 0.37% |
| VANGUARD FIDUCIARY TRUST CO | 05/08/2026 | 154.48 K | $3.71 M | 100.00% | 0.35% |
| MILLENNIUM MANAGEMENT LLC | 05/15/2026 | 124.10 K | $2.98 M | 15.48% | 0.28% |
| UBS GROUP AG | 05/05/2026 | 116.98 K | $2.81 M | 69.99% | 0.26% |
| MORGAN STANLEY | 05/15/2026 | 110.53 K | $2.66 M | 6.29% | 0.25% |
| HUSSMAN STRATEGIC ADVISORS, INC. | 05/11/2026 | 105.00 K | $2.52 M | 100.00% | 0.24% |
| CHECKPOINT CAPITAL L.P. | 05/15/2026 | 100.30 K | $2.41 M | 100.00% | 0.23% |
| FEDERATED HERMES, INC. | 05/11/2026 | 89.30 K | $2.15 M | 13.18% | 0.20% |
| JPMORGAN CHASE & CO | 05/13/2026 | 84.67 K | $1.97 M | 23.90% | 0.19% |
| INVESCO LTD. | 05/12/2026 | 82.87 K | $1.99 M | -48.85% | 0.19% |
| TWO SIGMA INVESTMENTS, LP | 05/15/2026 | 75.37 K | $1.81 M | -18.79% | 0.17% |
| LONGAEVA PARTNERS L.P. | 05/15/2026 | 74.57 K | $1.79 M | 49.43% | 0.17% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 05/15/2026 | 73.00 K | $1.75 M | 5.49% | 0.16% |
| AMERICAN CENTURY COMPANIES INC | 05/15/2026 | 61.29 K | $1.47 M | 20.91% | 0.14% |
| BANK OF NEW YORK MELLON CORP | 05/05/2026 | 58.71 K | $1.41 M | 6.10% | 0.13% |
| JUMP FINANCIAL, LLC | 05/14/2026 | 53.01 K | $1.27 M | 531.16% | 0.12% |
| SOFINNOVA INVESTMENTS, INC. | 05/15/2026 | 47.51 K | $1.14 M | 100.00% | 0.11% |
| MARSHALL WACE, LLP | 05/15/2026 | 39.84 K | $957.35 K | -82.44% | 0.09% |
| RANGELEY CAPITAL, LLC | 05/15/2026 | 39.80 K | $956.39 K | -39.51% | 0.09% |
| RENAISSANCE TECHNOLOGIES LLC | 05/14/2026 | 37.70 K | $905.93 K | 100.00% | 0.09% |
| XTX TOPCO LTD | 05/15/2026 | 36.72 K | $882.45 K | 57.51% | 0.08% |
| TREXQUANT INVESTMENT LP | 05/15/2026 | 35.30 K | $848.28 K | -19.78% | 0.08% |
| ALYESKA INVESTMENT GROUP, L.P. | 05/15/2026 | 35.00 K | $841.05 K | 0.00% | 0.08% |
| ACADIAN ASSET MANAGEMENT LLC | 05/13/2026 | 30.98 K | $741.00 K | 0.33% | 0.07% |
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Septerna Inc. institutional Ownership - FAQ's
During the previous two years, 148 institutional investors and hedge funds held shares of Septerna Inc.. The most heavily invested institutionals were:
RA CAPITAL MANAGEMENT, L.P.: 7 M
TRV GP V, LLC: 6.22 M
DRIEHAUS CAPITAL MANAGEMENT LLC: 4.4 M
TRV GP VI, LLC: 4.21 M
Samsara BioCapital, LLC: 3.15 M
GOLDMAN SACHS GROUP INC: 2.91 M
103.31% of Septerna Inc. stock is owned by institutional investors.
Institutional investors have bought a total of 45.70 M shares in the last 24 months. This purchase volume represents approximately $1.33 B in transactions.