Septerna Inc. Major Shareholders & Ownership History
| Major Shareholder Name | Reporting Date | Shares Held | Market Value | Change in Shares | Ownership |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 08/14/2026 | 7.00 M | $234.29 M | 0.00% | 15.53% |
| TRV GP V, LLC | 08/10/2026 | 6.22 M | $208.16 M | 0.00% | 13.80% |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 08/14/2026 | 4.43 M | $148.46 M | 0.85% | 9.84% |
| TRV GP VI, LLC | 08/10/2026 | 4.21 M | $141.05 M | 0.00% | 9.35% |
| SAMSARA BIOCAPITAL, LLC | 08/14/2026 | 3.15 M | $105.46 M | 0.00% | 6.99% |
| GOLDMAN SACHS GROUP INC | 08/14/2026 | 3.06 M | $102.57 M | 5.38% | 6.80% |
| BLACKROCK, INC. | 08/07/2026 | 1.93 M | $64.71 M | 6.03% | 4.29% |
| SIREN, L.L.C. | 08/13/2026 | 1.90 M | $63.63 M | -5.00% | 4.22% |
| AVORO CAPITAL ADVISORS LLC | 08/14/2026 | 1.34 M | $44.79 M | 0.00% | 2.97% |
| JUPITER TOPCO LLC | 08/14/2026 | 1.31 M | $43.72 M | 100.00% | 2.90% |
| VANGUARD CAPITAL MANAGEMENT LLC | 08/13/2026 | 1.22 M | $40.91 M | 2.06% | 2.71% |
| PRIMECAP MANAGEMENT CO/CA/ | 08/14/2026 | 1.17 M | $39.10 M | 11.30% | 2.59% |
| FIRST LIGHT ASSET MANAGEMENT, LLC | 08/14/2026 | 963.26 K | $32.26 M | 31.44% | 2.14% |
| ADAR1 CAPITAL MANAGEMENT, LLC | 08/14/2026 | 940.75 K | $31.51 M | -13.68% | 2.09% |
| GEODE CAPITAL MANAGEMENT, LLC | 08/12/2026 | 679.16 K | $22.75 M | 5.27% | 1.51% |
| STATE STREET CORP | 08/07/2026 | 652.63 K | $21.86 M | 3.35% | 1.45% |
| LOOMIS SAYLES & CO L P | 08/14/2026 | 624.75 K | $20.92 M | 100.00% | 1.39% |
| CASDIN CAPITAL, LLC | 08/14/2026 | 553.27 K | $18.53 M | 0.00% | 1.23% |
| CATALIO CAPITAL MANAGEMENT, LP | 08/14/2026 | 536.15 K | $17.96 M | 82.14% | 1.19% |
| CAPTION MANAGEMENT, LLC | 08/14/2026 | 440.00 K | $14.74 M | 100.00% | 0.98% |
| ALGERT GLOBAL LLC | 08/13/2026 | 397.49 K | $13.31 M | 1,789.65% | 0.88% |
| BALYASNY ASSET MANAGEMENT L.P. | 08/14/2026 | 350.44 K | $11.74 M | 48.07% | 0.78% |
| LONGAEVA PARTNERS L.P. | 08/14/2026 | 298.17 K | $9.99 M | 299.87% | 0.66% |
| SOLEUS CAPITAL MANAGEMENT, L.P. | 08/11/2026 | 275.00 K | $9.21 M | 0.00% | 0.61% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 08/14/2026 | 262.00 K | $8.77 M | 258.90% | 0.58% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 08/13/2026 | 230.18 K | $7.71 M | 18.02% | 0.51% |
| UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH | 08/06/2026 | 222.70 K | $7.46 M | -0.58% | 0.49% |
| TWO SIGMA INVESTMENTS, LP | 08/14/2026 | 220.89 K | $7.40 M | 193.08% | 0.49% |
| NORTHERN TRUST CORP | 08/13/2026 | 201.13 K | $6.74 M | 22.25% | 0.45% |
| TUDOR INVESTMENT CORP ET AL | 08/14/2026 | 200.00 K | $6.70 M | 100.00% | 0.44% |
| CAPTION MANAGEMENT, LLC | 08/14/2026 | 200.00 K | $6.70 M | 100.00% | 0.44% |
| KALEHUA CAPITAL MANAGEMENT LLC | 08/19/2026 | 194.54 K | $6.52 M | 0.00% | 0.43% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 08/14/2026 | 187.04 K | $6.26 M | 3.01% | 0.42% |
| SIXTH STREET PARTNERS MANAGEMENT COMPANY, L.P. | 08/14/2026 | 187.04 K | $6.26 M | 100.00% | 0.42% |
| WOODLINE PARTNERS LP | 08/14/2026 | 185.54 K | $6.21 M | 100.00% | 0.41% |
| VANGUARD FIDUCIARY TRUST CO | 08/13/2026 | 165.66 K | $5.55 M | 7.23% | 0.37% |
| MORGAN STANLEY | 08/13/2026 | 134.38 K | $4.50 M | 21.58% | 0.30% |
| TUDOR INVESTMENT CORP ET AL | 08/14/2026 | 100.00 K | $3.35 M | 100.00% | 0.22% |
| UBS GROUP AG | 08/13/2026 | 89.87 K | $3.01 M | -23.17% | 0.20% |
| FEDERATED HERMES, INC. | 08/12/2026 | 86.75 K | $2.91 M | -2.85% | 0.19% |
| JPMORGAN CHASE & CO | 08/12/2026 | 85.30 K | $2.96 M | 0.74% | 0.19% |
| CITADEL ADVISORS LLC | 09/02/2026 | 81.80 K | $2.74 M | 100.00% | 0.18% |
| LAZARD ASSET MANAGEMENT LLC | 08/14/2026 | 75.43 K | $2.53 M | 100.00% | 0.17% |
| DIMENSIONAL FUND ADVISORS LP | 08/11/2026 | 75.31 K | $2.52 M | 100.00% | 0.17% |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 08/13/2026 | 74.65 K | $2.50 M | 100.00% | 0.17% |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 08/14/2026 | 68.18 K | $2.28 M | 139.77% | 0.15% |
| HUSSMAN STRATEGIC ADVISORS, INC. | 08/03/2026 | 63.00 K | $2.11 M | -40.00% | 0.14% |
| AMERICAN CENTURY COMPANIES INC | 08/12/2026 | 60.97 K | $2.04 M | -0.52% | 0.14% |
| DIADEMA PARTNERS LP | 08/14/2026 | 59.70 K | $2.00 M | 100.00% | 0.13% |
| JANE STREET GROUP, LLC | 08/14/2026 | 57.20 K | $1.92 M | 100.00% | 0.13% |
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Septerna Inc. institutional Ownership - FAQ's
During the previous two years, 179 institutional investors and hedge funds held shares of Septerna Inc.. The most heavily invested institutionals were:
RA CAPITAL MANAGEMENT, L.P.: 7 M
TRV GP V, LLC: 6.22 M
DRIEHAUS CAPITAL MANAGEMENT LLC: 4.43 M
TRV GP VI, LLC: 4.21 M
Samsara BioCapital, LLC: 3.15 M
GOLDMAN SACHS GROUP INC: 3.06 M
105.31% of Septerna Inc. stock is owned by institutional investors.
Institutional investors have bought a total of 49.91 M shares in the last 24 months. This purchase volume represents approximately $1.45 B in transactions.