Major Shareholders & Ownership History
| Major Shareholder Name | Reporting Date | Shares Held | Market Value | Change in Shares | Ownership |
|---|---|---|---|---|---|
| QVT FINANCIAL LP | 02/13/2026 | 4.62 M | $10.61 M | 0.00% | 6.67% |
| ORBIMED ADVISORS LLC | 02/17/2026 | 4.17 M | $10.08 M | 0.00% | 6.02% |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 02/17/2026 | 3.70 M | $8.95 M | 0.00% | 5.35% |
| ACUTA CAPITAL PARTNERS, LLC | 02/17/2026 | 3.41 M | $8.25 M | 0.00% | 4.93% |
| AVORO CAPITAL ADVISORS LLC | 03/16/2026 | 2.85 M | $6.90 M | 0.00% | 4.12% |
| 02/18/2026 | 2.17 M | $5.24 M | 100.00% | 3.13% | |
| SIREN, L.L.C. | 02/13/2026 | 2.08 M | $5.04 M | 0.00% | 3.01% |
| YU FAN | 02/18/2026 | 2.07 M | $5.01 M | 0.00% | 2.99% |
| VANGUARD GROUP INC | 01/29/2026 | 1.59 M | $3.85 M | 18.41% | 2.30% |
| STEMPOINT CAPITAL LP | 02/17/2026 | 1.46 M | $3.53 M | 243.99% | 2.11% |
| ACORN CAPITAL ADVISORS, LLC | 02/17/2026 | 1.14 M | $2.76 M | 0.00% | 1.65% |
| ALLY BRIDGE GROUP (NY) LLC | 02/17/2026 | 817.94 K | $1.98 M | 0.00% | 1.18% |
| RENAISSANCE TECHNOLOGIES LLC | 02/12/2026 | 440.72 K | $1.07 M | -3.65% | 0.64% |
| GEODE CAPITAL MANAGEMENT, LLC | 02/09/2026 | 425.44 K | $1.03 M | 11.44% | 0.61% |
| TWO SIGMA INVESTMENTS, LP | 02/17/2026 | 309.87 K | $749.87 K | 100.00% | 0.45% |
| BLACKROCK, INC. | 02/12/2026 | 299.01 K | $723.61 K | 0.96% | 0.43% |
| EVERSEPT PARTNERS, LP | 02/17/2026 | 260.26 K | $629.83 K | 100.00% | 0.38% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 02/17/2026 | 215.28 K | $520.99 K | 0.00% | 0.31% |
| STATE STREET CORP | 02/13/2026 | 145.54 K | $352.20 K | 111.73% | 0.21% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 02/17/2026 | 110.08 K | $266.40 K | 100.00% | 0.16% |
| NORTHERN TRUST CORP | 02/17/2026 | 103.45 K | $250.35 K | 43.36% | 0.15% |
| CITADEL ADVISORS LLC | 02/17/2026 | 98.95 K | $239.46 K | -29.43% | 0.14% |
| ADAR1 CAPITAL MANAGEMENT, LLC | 02/18/2026 | 77.59 K | $187.78 K | 100.00% | 0.11% |
| QUBE RESEARCH & TECHNOLOGIES LTD | 02/17/2026 | 72.35 K | $175.08 K | 100.00% | 0.10% |
| JANE STREET GROUP, LLC | 02/12/2026 | 69.93 K | $169.23 K | 177.34% | 0.10% |
| MARSHALL WACE, LLP | 02/13/2026 | 67.96 K | $164.46 K | 100.00% | 0.10% |
| TWO SIGMA ADVISERS, LP | 02/17/2026 | 42.40 K | $102.61 K | 100.00% | 0.06% |
| UBS GROUP AG | 01/29/2026 | 29.84 K | $72.22 K | 424.22% | 0.04% |
| DIMENSIONAL FUND ADVISORS LP | 02/12/2026 | 28.64 K | $69.31 K | -35.08% | 0.04% |
| ABG INNOVATION CAPITAL PARTNERS III GP LTD | 02/17/2026 | 26.67 K | $64.53 K | 0.00% | 0.04% |
| ACADIAN ASSET MANAGEMENT LLC | 02/10/2026 | 24.63 K | $58.00 K | -6.00% | 0.04% |
| PRELUDE CAPITAL MANAGEMENT, LLC | 02/17/2026 | 18.80 K | $45.49 K | 100.00% | 0.03% |
| XTX TOPCO LTD | 02/17/2026 | 15.70 K | $38.00 K | -20.61% | 0.02% |
| QUADRATURE CAPITAL LTD | 02/17/2026 | 11.45 K | $27.70 K | 100.00% | 0.02% |
| MORGAN STANLEY | 02/13/2026 | 6.75 K | $16.33 K | 264.95% | 0.01% |
| US BANCORP \DE\ | 01/30/2026 | 3.33 K | $8.07 K | 0.00% | 0.00% |
| ADVISOR GROUP HOLDINGS, INC. | 02/17/2026 | 3.07 K | $7.43 K | 0.00% | 0.00% |
| BARTLETT & CO. WEALTH MANAGEMENT LLC | 01/22/2026 | 1.33 K | $3.23 K | 0.00% | 0.00% |
| 01/30/2026 | 1.25 K | $3.04 K | 100.00% | 0.00% | |
| BANK OF AMERICA CORP /DE/ | 02/17/2026 | 411 | $995 | 793.48% | 0.00% |
| RUSSELL INVESTMENTS GROUP, LTD. | 02/17/2026 | 386 | $934 | 0.00% | 0.00% |
| TD WATERHOUSE CANADA INC. | 01/27/2026 | 232 | $561 | 0.00% | 0.00% |
| BNP PARIBAS ARBITRAGE, SNC | 02/10/2026 | 160 | $387 | 0.00% | 0.00% |
| JPMORGAN CHASE & CO | 02/11/2026 | 121 | $293 | -71.26% | 0.00% |
| GROUP ONE TRADING, L.P. | 02/12/2026 | 100 | $242 | 100.00% | 0.00% |
| SBI SECURITIES CO., LTD. | 02/03/2026 | 19 | $46 | 0.00% | 0.00% |
| PARALLEL ADVISORS, LLC | 02/11/2026 | 8 | $19 | 0.00% | 0.00% |
| STONEPINE CAPITAL MANAGEMENT, LLC | 02/13/2026 | 0 | $0 | -100.00% | 0.00% |
| TOWER RESEARCH CAPITAL LLC (TRC) | 02/17/2026 | 0 | $0 | -100.00% | 0.00% |
| SQUAREPOINT OPS LLC | 02/13/2026 | 0 | $0 | -100.00% | 0.00% |
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institutional Ownership - FAQ's
During the previous two years, 52 institutional investors and hedge funds held shares of . The most heavily invested institutionals were:
QVT Financial LP: 4.62 M
ORBIMED ADVISORS LLC: 4.17 M
SUVRETTA CAPITAL MANAGEMENT, LLC: 3.7 M
ACUTA CAPITAL PARTNERS, LLC: 3.41 M
Avoro Capital Advisors LLC: 2.85 M
Siren, L.L.C.: 2.08 M
47.65% of stock is owned by institutional investors.
Institutional investors have bought a total of 31.63 M shares in the last 24 months. This purchase volume represents approximately $0 in transactions.